Category: News

Genome-wide transcriptome study of African swine fever virus

Scientists from The Pirbright Institute and University College London (UCL) have mapped the expression of genes across the entire African swine fever virus (ASFV) genome, which has helped to establish their order of activation as well as uncovering new genes. In their study, published in the Journal of Virology, the researchers used next generation sequencing […]

Ear implant delivers anaplasmosis vaccine to cattle

Researchers at the Kansas State University, in collaboration with Iowa State University, have developed a new vaccine delivery platform to produce long-lasting protection against bovine anaplasmosis. The results of their study are published in the Journal of Animal Science. “Currently, a common strategy to control anaplasmosis is to provide mineral or feed containing the antibiotic […]

Nipah vaccine candidates generate a strong immune response in pigs

Scientists at The Pirbright Institute have shown that two new potential vaccines against Nipah virus developed by the University of Parma generate a strong immune response in pigs. These promising results suggest the vaccines could protect pigs against Nipah virus infection, which can cause respiratory problems and fatal encephalitis in pigs and humans. By preventing […]

Epidemiological analyses of African swine fever in the European Union

The European Food Safety Authority (EFSA) has published its latest annual update on the presence of African swine fever (ASF) in the European Union. During the period covered by the report – November 2018 to October 2019 – Czechia became officially ASF-free. The disease was, however, confirmed as present in Slovakia, meaning there continue to […]

Resilience to bovine TB traced to key genes

Researchers have mapped active and inactive genes in bovine alveolar macrophages (bAM), which play a key role in countering bovine tuberculosis (bTB) infections. The findings of the study, led by scientists at University College Dublin (UCD) in collaboration with The Roslin Institute, are published in Frontiers in Genetics. In order to map which genes in […]

Bluetongue virus strain and origin in 2016 Cyprus outbreak determined

In September 2016, suspected cases of bluetongue in sheep were simultaneously reported in three different locations in Cyprus. Scientists at the European Union Reference Laboratory for Bluetongue (EURL-BT) at The Pirbright Institute confirmed that BTV-8 was present in all samples submitted by the National Reference Laboratory in Nicosia, Cyprus. This was the first time that […]

Experimental vaccine for African swine fever virus shows promise

Researchers have discovered a previously uncharacterized virus gene, which when deleted completely attenuates the Georgia isolate (ASFV-G) of African swine fever virus. Animals infected with this genetically modified virus were protected from developing ASF after challenge with the virulent parental virus. The findings are reported in the Journal of Virology. In the study, both low […]

Study finds Porcine deltacoronavirus is easily transmitted among chickens and turkeys

Experimental Porcine deltacoronavirus (PDCoV) infection and subsequent transmission among poultry is reported in Emerging Infectious Diseases. The Ohio State University researchers who led this work were part of a team that previously found in a laboratory setting that the virus could infect cells from multiple species, including chickens and humans. In the latest study, birds […]

Research sheds new light on molecular evolution of Foot-and-mouth disease virus

Research from The Pirbright Institute has shown that different populations of Foot-and-mouth disease virus (FMDV) swap sections of genetic material at a far higher rate than originally thought. It was previously believed that FMDV evolution is mainly driven by mutations caused by small copying errors that accumulate in the RNA genome of the virus when […]

Genetic engineering speeds up poultry vaccine development

Scientists at The Pirbright Institute have used genetic engineering to develop a vaccine that protects birds against both Marek’s disease and avian influenza. They say the process is faster and more efficient compared to previous methods, which will allow poultry vaccine producers to rapidly update vaccine strains in order to keep up with virus evolution. […]