Tag: African swine fever virus
Modified virus shows promise as an ASF vaccine
Researchers have found that deleting a gene of African swine fever virus (ASFV) reduces its ability to cause infection and protects against a strain of the virus that causes severe disease. In the study, published in the Journal of Virology, scientists at The Pirbright Institute deleted an ASFV gene that codes for a protein (DP148R) thought […]
Unique structure of ASFV enzyme may allow drug development
A DNA-copying protein from African swine fever virus (ASFV) has a unique structure that may offer a target for drugs, according to a study published in PLoS Biology by Yiqing Chen and colleagues at Fudan University in Shanghai, China. Viral replication depends in part on a polymerase enzyme, AsfvPolX, that repairs breaks in the DNA, […]