Tag: vaccines
Model predicts effectiveness of livestock vaccines
Scientists at The Roslin Institute have developed an epidemiological model to investigate the effectiveness of vaccines for preventing, mitigating or eliminating infectious diseases in livestock. When appropriately applied, even imperfect vaccines can prevent, eliminate or largely reduce the prevalence of viruses, the model shows. The goal of effective vaccination is not only to protect individuals […]
Developing a peptide-based vaccine for Johne’s disease
Researchers are investigating the possibility of developing a peptide-based vaccine for Mycobacterium avium subspecies paratuberculosis (MAP). Vaccinating animals with dead MAP cells can generate misleading false-positive results when vaccinated cattle are tested for bovine tuberculosis. An alternative approach could come from vaccinating the animals with specific pieces of MAP rather than using the entire bacterium, […]
Infectious bronchitis vaccines: study highlights the need for targeted genetic modification of viruses
Scientists at The Pirbright Institute have shown that Infectious bronchitis virus (IBV) vaccines produced in eggs have unpredictable mutations which may be prone to reversion in the field. Live attenuated vaccines, where IBV is weakened so that it causes less severe or no disease, are used in the field as they offer better protection compared […]
ASFV vaccine candidate tested in wild boar
An article published in Frontiers in Veterinary Science describes the experimental vaccination of wild boar against African swine fever virus (ASFV). Oral immunization of wild boar with a non-haemadsorbing, attenuated ASFV of genotype II conferred 92% protection against challenge with a virulent ASF virus isolate (Arm07). “African swine fever is of enormous concern to the […]
Vaccinology in Africa Course, 29 April – 3 May 2019, Banjul, The Gambia
Applications now open African VaccinologyThe course is aimed at students, researchers and professionals resident in Africa and cover the main aspects of vaccinology, vaccine development process, biomanufacturing, regulatory and ethical issues. The course has an exceptional faculty of academic and industrial speakers, and resonates with the ‘One Health’ agenda. Participants are selected on their direct […]
Strategies to increase adoption of animal vaccines by smallholder farmers
An article in PLOS Neglected Tropical Diseases outlines strategies that can be used to increase the adoption of animal vaccines by smallholder farmers in Africa, Asia, and Latin America, with focus on the control of neglected tropical diseases, particularly neglected zoonotic diseases (NZDs). The authors – Meritxell Donadeu, Nick Nwankpa, Bernadette Abela-Ridder and Baptiste Dungu […]
EuFMD-IVVN workshop
The European Commission for the Control of Foot-and-Mouth Disease (EuFMD) are hosting a workshop funded by the IVVN on ‘Field evaluation of novel livestock vaccines’. The focus of the workshop will be on study designs for vaccine field trials and the practical aspects of their implementation. Presentations will be delivered by expert guest speakers and […]
Two PPRV vaccines protect against all strains
Scientists at The Pirbright Institute have conducted a study to directly compare the ability of two vaccines to protect susceptible animals against wildtype viruses from any of the four genetic lineages of Peste-des-petits-ruminants virus (PPRV). Through analysing the immune response of goats that were administered the vaccines, they were able to demonstrate that both vaccines […]
Creating FMDV hybrids for better vaccines
In collaborative research led by The Pirbright Institute, scientists have generated a hybrid Foot-and-mouth disease virus (FMDV) with improved stability, which will increase its effectiveness when administered as a vaccine. They targeted the Southern African Territories (SAT) 2 serotype viruses, which are among the least stable of the seven different types of FMDV. Developing vaccines […]