“Global Strategic Alliances for the Coordination of Research on the Major Infectious Diseases of Animals and Zoonoses”

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Novel antibiotic resistance gene in milk

Researchers at the University of Bern have identified a new antibiotic resistance gene in Macrococcus caseolyticus strains from dairy cows. This gene confers resistance to all beta-lactam antibiotics including the last generation of cephalosporins used against methicillin-resistant Staphylococcus aureus (MRSA). A transfer to S. aureus (which is possible according to the researchers) would jeopardize the use of reserve antibiotics to treat human infections caused by multidrug-resistant bacteria in hospitals. Macrococcus caseolyticus is a harmless bacterium naturally found on the skin of dairy cows which can spread to milk during the milking process. It can also be present in dairy products made from raw milk. The researchers investigated M. caseolyticus present in milk of dairy cows suffering from mastitis. These strains showed an unusual resistance pattern to beta-lactam antibiotics [...]

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Unique structure of ASFV enzyme may allow drug development

A DNA-copying protein from African swine fever virus (ASFV) has a unique structure that may offer a target for drugs, according to a study published in PLoS Biology by Yiqing Chen and colleagues at Fudan University in Shanghai, China. Viral replication depends in part on a polymerase enzyme, AsfvPolX, that repairs breaks in the DNA, but the structure of this enzyme has not been determined in detail. The authors used X-ray diffraction and nuclear magnetic resonance to solve the structure at atomic resolution. The team found that the enzyme contained a unique binding pocket for the building blocks of DNA (nucleotides), not seen in related enzymes in other organisms. They also found several other unique structural features, including a pair of hydrophobic amino acids that interact with incoming [...]

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Gene editing for PRRSV resistance in pigs

Precision engineering renders target cells of PRRSV resistant to infection with the virus. Researchers have used advanced genetic techniques to produce pigs that are potentially resilient to Porcine reproductive and respiratory syndrome (PRRS). Early tests have revealed that cells from the pigs are completely resistant to infection with both major subtypes of the virus that causes the disease. The animals are otherwise healthy and the change – introduced using gene editing technology – should not affect their ability to fight off other infections, the researchers say. Studies have shown that the PRRS virus targets macrophages. A molecule on the surface of these cells called CD163 plays a key role in enabling the PRRS virus to establish an infection. The research team at the University of Edinburgh’s Roslin Institute, [...]

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Call for Interest on Designation as FAO Reference Centre for Antimicrobial Resistance (AMR)

Members of the Food and Agriculture Organization (FAO) committed at the 39th Session of the FAO Conference (June 2015) to work on the issue of Antimicrobial Resistance (AMR) through Resolution 4/2015. The resolution calls upon both FAO members and the organization itself to address the threat posed by AMR to public health, agriculture production and food safety and security. The FAO Resolution on AMR highlights the support of the food and agriculture sector to implement the Global Action Plan (GAP) on AMR which was developed by the World Health Organization in collaboration with FAO and the World Organisation for Animal Health. In 2016, the FAO Action Plan on Antimicrobial Resistance 2016 – 2020 was developed and published outlining the role of FAO on implementing the GAP. Four focus [...]

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8th International Conference on Emerging Zoonoses

8th International Conference on Emerging Zoonoses with an emphasis on Emerging and Transboundary Infectious Diseases, which will take place in Manhattan, Kansas, May 7 – 10, 2017. There is a significantly raised awareness that zoonoses and transboundary diseases threaten both human and animal health. Therefore, research and policy should focus on a “One Health” perspective in local, national, and international environments. To properly address these issues, the conference plans to have special workshops which will be organized by experts in their fields. Potential topics might include:  the ecology of emerging zoonotic and transboundary diseases; the role of wildlife in emerging zoonoses and transboundary diseases; cross-species transmission of zoonotic and transboundary pathogens; emerging and neglected influenza viruses; hemorrhagic fever viruses; emerging and transboundary bacterial diseases; outbreak responses to zoonotic [...]

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American Academy of Veterinary Pharmacology and Therapeutics (AAVPT) 2oth Biennial Symposium

The theme for this year’s AAVPT biennial meeting is “The Role of Veterinary Pharmacology in One Health.” It explore the multifaceted challenges faced as veterinary pharmacologists seek to meet the therapeutic needs associated with veterinary species while engaging in efforts to better understand the commonality in physiology, pharmacokinetics, and disease targets that define our One World Health. www.aavpt.org/page/20Biennial

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IX Conferencia Anual Vet+i

IX Conferencia Anual de la Fundación Vet+i-Plataforma Tecnológica Española de Sanidad Animal “Los beneficios para la sociedad de la I+D+i en Sanidad Animal” http://www.vetmasi.es/vetmasi-conferencia-anual/eventos/ix-conferencia-anual-vet+i_3633_15_3749_0_1_in.html Contact: secretaria@vetmasi.es

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4th International Symposium on Ranaviruses

4th International Ranavirus Symposium to be held in Budapest from June 7th-10th, 2017. This meeting will be held in conjunction with the 10th International Symposium on Viruses of Lower Vertebrates (ISVLV) from June 4th to 7th. We are very excited about hosting these meetings and we hope that many of you will come and participate. The venue of the meeting is the historical campus of the University of Veterinary Science, Budapest in the heart of the city of Pest. http://www.rana-2017,com

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One Health: 9th Tick and Tick-borne Pathogen Conference & 1st Asia Pacific Rickettsia Conference

Ticks and tick-borne pathogens, including rickettsiae, are important causes of ill health in animals and humans in the Asia-Pacific region. This conference is of interest to veterinarians, medical doctors, public health professionals, epidemiologists, acarologists, diagnostic laboratory personnel, and vaccine producers. Conference themes are: One health [conference theme] Genetics/genomics Epidemiology, Ecology & Modelling Diagnostics & Treatment Immunity & Vaccines Infection & Pathogenesis Taxonomy & Evolution Zoonoses Conference Organising Committee A/Prof Ala Lew-Tabor (Chairperson, Convenor TTP9) Prof. Stephen Graves (Convenor APRC1) A/Prof John Stenos (Convenor APRC1) Dr Manuel Rodriguez Valle (Convenor TTP9) http://www.ttp9-aprc1.com/  

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33rd World Veterinary Congress, Incheon, Korea (South)

The 33rd World Veterinary Congress is aimed at promoting and raising awareness about One Health, an emerging concept that encompasses the health of humans, animals and their environment, across the globe as well as sharing New Wave of the New Technologies in all disciplines of clinical veterinary medicine and creating a new trend in the field. www.wvc2017korea.com

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