“Global Strategic Alliances for the Coordination of Research on the Major Infectious Diseases of Animals and Zoonoses”

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NEWS

Bats are the major reservoir of coronaviruses worldwide

Results of a five-year study in 20 countries on three continents have found that bats harbour a large diversity of coronaviruses (CoV). Findings from the study – led by scientists in the USAID-funded PREDICT project at the Center for Infection and Immunity (CII) at Columbia University’s Mailman School of Public Health and the University of California, Davis’ One Health Institute in the School of Veterinary Medicine – are published in the journal Virus Evolution. PREDICT is a globally coordinated effort to detect and discover viruses of pandemic potential and reduce risk for future epidemics. With the cooperation of local governments, researchers sampled and tested 19,192 bats, rodents, non-human primates, and humans in areas where the risk of animal-to-human transmission is greatest, including sites of deforestation, ecotourism, and animal [...]

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Pandemic potential of H9N2 avian influenza viruses studied

Researchers have identified the molecular mechanisms that enable H9N2 viruses – the most common type of avian influenza virus – to infect humans, helping improve risk assessments for its potential to cause pandemic. Although H9N2 viruses are considered less pathogenic than some types of avian influenza virus, they still cause significant losses for the poultry industry in many countries throughout Asia, the Middle East and North Africa – sometimes with death rates as high as 60%. Over the past 20 years there have also been a growing number of (generally mild) human infections of H9N2 in Hong Kong, mainland China, Bangladesh and Egypt, especially amongst poultry workers. Concerns increased however when other experiments demonstrated the potential for human-to-human airborne transmission; a property normally associated with the potential to [...]

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Novel antibiotic resistance gene in milk

Researchers at the University of Bern have identified a new antibiotic resistance gene in Macrococcus caseolyticus strains from dairy cows. This gene confers resistance to all beta-lactam antibiotics including the last generation of cephalosporins used against methicillin-resistant Staphylococcus aureus (MRSA). A transfer to S. aureus (which is possible according to the researchers) would jeopardize the use of reserve antibiotics to treat human infections caused by multidrug-resistant bacteria in hospitals. Macrococcus caseolyticus is a harmless bacterium naturally found on the skin of dairy cows which can spread to milk during the milking process. It can also be present in dairy products made from raw milk. The researchers investigated M. caseolyticus present in milk of dairy cows suffering from mastitis. These strains showed an unusual resistance pattern to beta-lactam antibiotics [...]

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Unique structure of ASFV enzyme may allow drug development

A DNA-copying protein from African swine fever virus (ASFV) has a unique structure that may offer a target for drugs, according to a study published in PLoS Biology by Yiqing Chen and colleagues at Fudan University in Shanghai, China. Viral replication depends in part on a polymerase enzyme, AsfvPolX, that repairs breaks in the DNA, but the structure of this enzyme has not been determined in detail. The authors used X-ray diffraction and nuclear magnetic resonance to solve the structure at atomic resolution. The team found that the enzyme contained a unique binding pocket for the building blocks of DNA (nucleotides), not seen in related enzymes in other organisms. They also found several other unique structural features, including a pair of hydrophobic amino acids that interact with incoming [...]

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EVENTS

One Health: 9th Tick and Tick-borne Pathogen Conference & 1st Asia Pacific Rickettsia Conference

Ticks and tick-borne pathogens, including rickettsiae, are important causes of ill health in animals and humans in the Asia-Pacific region. This conference is of interest to veterinarians, medical doctors, public health professionals, epidemiologists, acarologists, diagnostic laboratory personnel, and vaccine producers. Conference themes are: One health [conference theme] Genetics/genomics Epidemiology, Ecology & Modelling Diagnostics & Treatment Immunity & Vaccines Infection & Pathogenesis Taxonomy & Evolution Zoonoses Conference Organising Committee A/Prof Ala Lew-Tabor (Chairperson, Convenor TTP9) Prof. Stephen Graves (Convenor APRC1) A/Prof John Stenos (Convenor APRC1) Dr Manuel Rodriguez Valle (Convenor TTP9) http://www.ttp9-aprc1.com/  

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33rd World Veterinary Congress, Incheon, Korea (South)

The 33rd World Veterinary Congress is aimed at promoting and raising awareness about One Health, an emerging concept that encompasses the health of humans, animals and their environment, across the globe as well as sharing New Wave of the New Technologies in all disciplines of clinical veterinary medicine and creating a new trend in the field. www.wvc2017korea.com

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26th International Conference of the World Association for the Advancement of Veterinary Parasitology (WAAVP)

In conjunction with the 53rd Malaysian Society of the Parasitology & Tropical Medicine (MSPTM) Annual Conference. http://www.waavp2017kl.org  

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11th Annual Meeting EPIZONE ‘Crossing barriers’

The European Research Group for Epizootic Disease Diagnosis and Control: a stimulating scientific programme provided by invited speakers and selected oral and poster presentations on epizootic diseases of cattle, pigs, poultry, sheep, goats, fish and horses. Hosted by ANSES at the Cite des sciences in Paris

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United States Animal Health Association (USAHA) Annual Meeting

121st USAHA & 60th AAVLD (American Association of Veterinary Laboratory Diagnosticians) Annual Meeting – October 12-18, 2017 Town and Country Hotel ~ San Diego, California

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Rabies in the Americas

The Rabies in the Americas (RITA) meeting is an annual event that has been held since 1990. It has been hosted in many countries across the Americas. For many years, RITA has grown in popularity and prominence with delegates now coming from more than 20 countries across five continents. The meeting provides an opportunity for researchers, health professionals, international, national and local managers of rabies programs, wildlife biologists, laboratory personnel and other people interested in advancing knowledge of rabies surveillance, prevention and control, to meet each other, to share their successes and also to discuss the challenges to be met. http://www.rabiesintheamericas.org/home

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