Helminths (including anthelmintic resistance) roadmap:
Therapeutics
Roadmap for development of therapeutics for helminths
Download Helminths-Therapeutic-Tests-Roadmap7
Alternatives to animal testing
Next steps
- 2 Clinical testing
- 2A Efficacy
- 2B Quality
- 3 Risk assessment methodologies
- 3A Target animal
- 3B User
- 3C Residues
- 3D Environmental
- 5 Pharmacology
- 5A Drug design
- 5B PK/PD integration
- 5C Combination of drugs/API
- 5D Formulation delivery routes
- 8 Animal models
Alternatives to animal testing
Research Question
What are we trying to achieve and why? What is the problem we are trying to solve?
Research Gaps and Challenges
What are the scientific and technological challenges (knowledge gaps needing to be addressed)?
Solution Routes
What approaches could/should be taken to address the research question?
Dependencies
What else needs to be done before we can solve this need?
State Of the Art
Existing knowledge including successes and failures
Projects
What activities are planned or underway?
Single-nucleotide polymorphisms in the beta-tubulin gene and its relationship with treatment response to albendazole in human soil-transmitted helminths in Southern Mozambique
Planned Completion date 14/09/2022
Source Countries:
Netherlands
An integrated set of novel approaches to counter the emergence and proliferation of invasive and virulent soil-borne nematodes – Project part: Fostering nematode suppression in soils by cover crops and addition of biological antagonists in Organic Farming (NEM-EMERGE)
Planned Completion date 31/12/2027
Source Countries:
Denmark