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Mycoplasmas including CBPP/CCPP roadmap:
Vaccines

Research roadmap for contagious bovine pleuropneumonia (CBPP) vaccine development

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Identity of immunomodulators

Identity of immunomodulators

Research Question

  1. Identify Mmm molecules that may modulate the immune response to promote infection and survival.
  2. Deletion of immunomodulatory factors may help in the design of attenuated and subunit Mmm vaccines.

Research Gaps and Challenges

  1. Lack of assays to measure immunomodulatory molecules.

Solution Routes

  1. Computational approaches to identify candidate genes.
  2. Develop assays to measure immunologically active molecules.

Dependencies

  1. Computational approaches to identify candidate genes.
  2. Develop assays to measure immunologically active molecules.