Home Mycoplasmas including CBPP/CCPP [Cell mediated immunity] Cell mediated immunity
Mycoplasmas including CBPP/CCPP roadmap:
Vaccines

Research roadmap for contagious bovine pleuropneumonia (CBPP) vaccine development

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Cell mediated immunity

Cell mediated immunity

Research Question

  1. Identify antigen specific cell mediated immune responses to Mmm molecules as this should help in understanding mechanisms that lead to disease and immunity

Research Gaps and Challenges

  1. Lack of assays to measure functionally relevant immune responses.
  2. Lack of disease stage biomarkers.

Solution Routes

  1. Develop in vitro and in vivo options for evaluating host responses to infection.
  2. Passive transfer and cell depletion experiments.