Mycoplasmas including CBPP/CCPP roadmap:
Vaccines
Research roadmap for contagious bovine pleuropneumonia (CBPP) vaccine development
Download CBPP vaccine development roadmap finalA
Entry
Entry
Research Question
- Characterise host and Mmm molecules involved in establishing an infection as an improved understanding of this process should help design better vaccines.
Research Gaps and Challenges
- Lack of high-throughput assays to measure bacterial proliferation in the host or host-like conditions.
- Lack of standardized assays.
Solution Routes
- Knowledge on colonization to prevent infection and disease.
- Understanding and preventing the establishment of disease is likely to be more promising in moving towards any intervention.
State Of the Art
- Mmm is less capable of invading macrophages than bovis.
- Mmm specific antisera promotes phagocytosis and killing.
Projects
What activities are planned or underway?
Collaborative project: Stressless examination for pathogens associated with bovine respiratory disease complex Stressless fUtuRE – subproject B (SURE)
Planned Completion date 31/05/2024
Source Countries:
Denmark
Collaborative project: Stressless examination for pathogens associated with bovine respiratory disease complex Stressless fUtuRE – subproject A (SURE)
Planned Completion date 31/05/2024
Source Countries:
Denmark