Author: Rachel Wood

Rapid on-farm test developed for porcine epidemic diarrhea virus

Researchers at McMaster University (Ontario, Canada) have developed a new form of rapid test to detect porcine epidemic diarrhea virus (PEDV) in pigs that they say can be adapted to test for other pathogens, and in other animals. Their findings are published in the journal Angewandte Chemie. The test, created by biochemist Yingfu Li and […]

Study provides new insight into the immune pathogenesis of FMDV

Researchers at the Pirbright Institute and the Roslin Institute have discovered how foot-and-mouth disease virus (FMDV) interacts with immune cells in lymphoid tissues, helping the virus to persist in animals such as African buffalo. Their findings are reported in PLoS Pathogens. In studies in mice, they found that FMDV binds to follicular dendritic cells, which […]

PIG-PARADIGM project aims to reduce the need for antibiotics

Researchers from universities in Denmark, the United States and the Netherlands are collaborating on a project to improve intestinal resilience in developing piglets, with the aim of advancing knowledge on how to prevent bacterial infections and reducing the need for antimicrobials. The 5-year project, called Preventing Infection in the Gut of developing Piglets – and […]

Genetic locus linked to tolerance to East Coast fever

Researchers from the Centre for Tropical Livestock Genetics and Health (CTLGH), Roslin Institute, the International Livestock Research Institute (ILRI) and the University of Glasgow sought to understand whether regions of the cattle genome might predict the likelihood that an animal can survive East Coast fever, a disease caused by the parasite Theileria parva, transmitted by […]

Safety of ASFV vaccine candidate assessed

The U.S. Department of Agriculture’s Agricultural Research Service (ARS) has announced that a vaccine candidate for African Swine Fever (ASF) has passed an important safety test required for regulatory approval. The test is an important milestone as part of a series of safety studies. These new results, published in Viruses, show that USDA’s live attenuated […]

MicroRNAs in milk could aid early diagnosis of bovine mastitis

Researchers at the Roslin Institute have determined that levels of microRNAs (miRNAs) in milk could be used as an accurate way to detect inflammation before clinical signs of mastitis are visible, potentially enabling rapid intervention to limit the impact of disease. The findings are published in Scientific Reports. The researchers studied levels of four types […]

Vehicles play an important role in PRRSV transmission

Researchers from North Carolina State University modelled different potential transmission routes for porcine reproductive and respiratory syndrome virus (PRRSV), and found that vehicles used to move not only animals, but also farm workers and feed, can be carriers for disease spread. Their findings are published in Transboundary and Emerging Diseases. The researchers modelled nine modes […]

Enterococcus strains in probiotics may carry antimicrobial resistance genes

Researchers at Kansas State University have discovered that Enterococcus faecium strains, isolated from commercial probiotic products for pigs and cattle, may pose risk to serve as a source of transmitting antimicrobial resistance genes to other gut bacteria. Their study is published in the Journal of Animal Science. Raghavendra Amachawadi, assistant professor of food animal therapeutics […]

Infectious bronchitis virus: reverse genetics system aids vaccine development

Researchers from The Pirbright Institute working to improve vaccines for infectious bronchitis virus (IBV) have developed a reverse genetics system, based on the pathogenic IBV strain M41, to identify genes which can be targeted for rational attenuation. Current vaccines for IBV are created by serial passage of virulent IBV field isolates through embryonated hens’ eggs. […]

Model suggests gene editing combined with vaccination could eliminate PRRS

Some livestock diseases could potentially be eradicated by introducing a proportion of animals that are genetically resistant to disease due to gene editing into some vaccinated herds, research led by the Roslin Institute suggests. A modelling study focusing on porcine reproductive and respiratory syndrome (PRRS) is published in Proceedings of the National Academy of Sciences […]