Author: Rachel Wood

Are best practice principles of worm control being deployed at farm level?

Because of the increasing prevalence of drug resistant parasites, more sustainable approaches to worm control need to be deployed on farms to protect anthelmintic efficacy. These ‘best practice’ approaches include the appropriate application of dewormers and the use of evidence-based protocols involving diagnostics, to inform the need for anthelmintic treatments, alongside management practices designed to […]

Ruminant livestock are important hosts of Leptospira in northern Tanzania

Leptospirosis, which affects more than one million people worldwide each year, is known to be transmitted to humans from a wide range of animals. Now, researchers reporting in PLOS Neglected Tropical Diseases have discovered that more than 7 percent of the cattle and 1 percent of sheep and goats in local slaughterhouses in northern Tanzania […]

Cost and scale of field trials for bovine TB vaccine may make them unfeasible

Field trials for a vaccine to protect cattle against bovine tuberculosis (bovine TB) would need to involve 500 herds – potentially as many as 75,000-100,000 cattle – to demonstrate cost effectiveness for farmers, concludes a study published in eLife. Instead, the researchers suggest that the scale and cost of estimating the effect of a vaccine […]

Local immune response to Influenza studied in pigs

Researchers from The Pirbright Institute, University of Bristol, Cardiff University and University of Oxford have developed tools to show how CD8 (killer) T cells in pigs are recruited in large numbers in the lung after infection with influenza or aerosol vaccination. The tools can also be used to identify virus proteins that are recognised by […]

Porcine deltacoronavirus: potential for cross-species transmission?

Researchers have found that Porcine deltacoronavirus (PDCoV) efficiently infects cultured cells of other species, including humans and chickens. The discovery raises concerns about the potential for cross-species transmission. Researchers at The Ohio State University and Utrecht University collaborated to better understand the new virus and its potential reach. Their findings are published in PNAS. Porcine […]

Two new genetic groups of Foot-and-mouth disease virus identified

Researchers from The Pirbright Institute have examined the genetic material of Foot-and-mouth disease virus (FMDV) samples collected from eastern and southern Africa, and discovered two novel virus groups. Their findings are published in the journal Viruses. FMD viruses are categorised into seven different serotypes, out of which serotypes O, A and Southern African Territories (SAT) […]

Survival of ASFV and other viral pathogens in feed

Researchers have found that African swine fever virus (ASFV) could survive in a simulated Trans-Atlantic feed shipment. The study, published in PLOS ONE, evaluated the survival of ASFV and other important viral pathogens of livestock in animal feed ingredients imported into the United States under simulated transboundary conditions. The viruses were selected based on global […]

FMDV protein could be used for disease detection

Dr Stephen Berryman and Dr Toby Tuthill from The Pirbright Institute have collaborated with the MRC Laboratory of Molecular Biology and other research institutes to uncover a system used by foot-and-mouth disease virus (FMDV) to prevent antiviral signalling of infected cells. The discovery could allow scientists to detect animals that have been infected with FMDV […]

Characterization of Mycobacterium bovis in Mozambique

The most extensive study to date of the genetic diversity of Mycobacterium bovis isolates from Mozambique is reported in PLOS Neglected Tropical Diseases. Bovine tuberculosis (BTB) is of global concern for multiple reasons – the economic impact on animal production, the potential spread to wildlife, and the risk of transmission to humans. While BTB is […]

One Health study of tick-borne diseases in Mongolia

To better understand the epidemiology of tick-borne disease in Mongolia, a comprehensive seroprevalence study was conducted investigating exposure to Anaplasma spp. and spotted fever group (SFG) Rickettsia spp. in nomadic herders and their livestock across three provinces from 2014 to 2015. Dr. Michael von Fricken spent a year living in Ulaanbataar as a postdoc with […]