Coronaviruses roadmap:
Control Strategies
Roadmap for the development of disease control strategies for coronaviruses
Download 202410 Draft Coronavirus Disease control research roadmap FinalB
Livestock
Livestock
Research Question
- Mitigate the risk of the occurrence of new and existing coronaviruses causing severe diseases in livestock and/or potential zoonotic severe impact and/or spillover to wildlife
Research Gaps and Challenges
- It is difficult to predict what the next coronavirus capable of causing severe disease in livestock will be
- Limited knowledge on cross-species transmissions (especially at the wildlife-livestock interface). Data on several CoV in livestock are not monitored
- Vaccination strategy and approach varies between backyard and commercial poultry industries. This has an impact on viral shedding
- Animal management and housing strategies – co-habitation of livestock and handlers in low- or middle-resource regions means that there is risk of spillover/spillback
Solution Routes
- Surveillance programme for CoV genetic evolution
- Integration of one health approach into the surveillance of coronaviruses
State Of the Art
- Expression of DPP4 from various livestock species on BHK cells suggested a broad range of livestock animal groups as potential amplifying hosts of MERS-CoV. Kane et al. https://www.annualreviews.org/doi/full/10.1146/annurev-animal-020420-025011#_i7
- List of the main coronaviruses infecting farm animals https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537542/
Projects
What activities are planned or underway?
Intervention Strategies to Control Endemic and New Emerging and Re-Emerging Viral Diseases of Swine
Planned Completion date 04/10/2026
Source Countries:
United States
Pathogenesis of Swine Acute Diarrhea Syndrome Coronavirus
Planned Completion date 31/08/2026
Source Countries:
United States