Coronaviruses roadmap:
Diagnostic Tests
Roadmap for the development of diagnostic tests for coronaviruses
Download 202410 Draft Coronavirus Diagnostic Development_FinalB
Cell-mediated immunity
Cell-mediated immunity
Research Question
- Can T-cell immunity be used as a diagnostic tool for detection and surveillance for animals?
Research Gaps and Challenges
- Tests are time consuming and expensive
- Unclear understanding of cell-mediated immunity in some species the basic immunology is not well characterised
- High species-dependence
Solution Routes
- Development of relatively rapid T-cell assays
- In highly important cases, T-cell can be used in high-value samples
Dependencies
- Availability of new and rapid platform
- Specific knowledge in certain animal species
State Of the Art
T-cells, especially memory T-cells, play a crucial role in long-term immunity against SARS-CoV-2
Projects
What activities are planned or underway?
Veterinary Biocontained facility Network for excellence in animal infectiology research and experimentation
Planned Completion date 28/02/2023
Source Countries:
Europe
MOLECULAR PATHOGENESIS AND ADAPTATION OF SARS-COV-2 IN WHITE-TAILED DEER AND IMPLICATIONS FOR SPILLOVER TO CATTLE AND PIGS
Planned Completion date 14/06/2026
Source Countries:
United Kingdom