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Mycoplasmas including CBPP/CCPP roadmap:
Vaccines

Research roadmap for contagious bovine pleuropneumonia (CBPP) vaccine development

Download CBPP vaccine development roadmap final

11

Vector

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Dependencies

Next steps

  • 7 Vectored vaccines
  • 7A Safety
  • 7B Delivery route
  • 7C Delivery platform
  • 7D Efficacy in challenge model
Vector

Research Question

  1. Vectored antigen delivery systems may provoke stronger immune responses and be easier to manufacture and deliver than protein-based vaccines.

Research Gaps and Challenges

  1. Lack of in vitro assays to guide vector selection.

Solution Routes

  1. Structured assessment of available vector platforms for suitability to vector candidate vaccine antigens.

Dependencies

  1. Standardized cattle breed specific laboratory challenge models that reproduce CBPP caused by natural infection or are acceptable surrogates.

State Of the Art

  1. A few experimental vaccine antigens have been identified.

Projects

What activities are planned or underway?

Collaborative project: Stressless examination for pathogens associated with bovine respiratory disease complex Stressless fUtuRE – subproject B (SURE)

Planned Completion date 31/05/2024

Source Countries:

DenmarkIconDenmark

Collaborative project: Stressless examination for pathogens associated with bovine respiratory disease complex Stressless fUtuRE – subproject A (SURE)

Planned Completion date 31/05/2024

Source Countries:

DenmarkIconDenmark