Bovine tuberculosis (bTB)
Bovine tuberculosis (bTB)
Bovine tuberculosis is a chronic bacterial disease of cattle that can affect other species of mammals, caused by Mycobacterium bovis, a bacterium in the Mycobacterium tuberculosis complex of the family Mycobacteriaceae. It is a significant zoonosis that can spread to humans by inhaling aerosols or from drinking unpasteurized milk. Bovine tuberculosis is still common in less developed countries, and causes economic losses from livestock deaths, chronic disease and trade restrictions. Effective bovine TB vaccines are not currently available for cattle.
The Roadmap for the Development of candidate vaccines can be seen on this website by clicking the link to the right (or go directly to the Roadmaps page). The roadmap is planned to be reviewed at a workshop to be held alongside the International Conference on Mycobacterium bovis, in Galway, which has been postponed from 2020 to 7-10 June 2021.
The Global Research Alliance for Bovine Tuberculosis (GRAbTB) was started under the STAR-IDAZ project, to facilitate research cooperation and technical exchange on bovine tuberculosis (bTB). GRAbTB currently has 15 partners from Asia, Australasia, the Americas and Europe, and is looking to expand their network. The Strategic Goals of GRAbTB are to: Identify research opportunities and facilitate collaborations within the Alliance; Conduct strategic and multi-disciplinary research to better understand bovine TB; Develop new and improved tools to control bovine TB; Serve as a communication and technology sharing gateway for the global bovine TB research community and stakeholders; and Promote collaboration with the human TB research community.
For more information on GRAbTB see: GRAbTB
The current state of bovine TB research is covered in the Annual state-of-the art report on animal health research on IRC priorities.
Events
Recent Articles
- Development and challenges in animal tuberculosis vaccination.
- Tuberculosis vaccines for cattle.
- Zoonotic tuberculosis: a neglected disease in the Middle East and North Africa (MENA) region.
- Vaccination strategies in a potential use of the vaccine against bovine tuberculosis in infected herds.
- Does Mycobacterium tuberculosis var. bovis survival in the environment confound bovine tuberculosis control and eradication? A literature review.
- Development of a diagnostic compatible BCG vaccine against Bovine tuberculosis.
- Reconsidering Mycobacterium bovis as a proxy for zoonotic tuberculosis: a molecular epidemiological surveillance study.
- Role of abattoir monitoring in determining the prevalence of bovine tuberculosis: A systematic review and meta-analysis.
- A defined antigen skin test for the diagnosis of bovine tuberculosis.
- Methodology and preliminary results of a systematic literature review of ante-mortem and post-mortem diagnostic tests for bovine tuberculosis.
- Editorial: Bovine tuberculosis—international perspectives on epidemiology and management.
News
- Field trials for bovine TB cattle vaccine and skin test move to next phase
- Study shows Mycobacterium bovis risk from raw milk products
- Bovine TB: genetic contact tracing could help control outbreaks
- Tuberculosis: study sheds light on species-specific host-pathogen interactions
- Potential for genetic control of bovine tuberculosis in Africa
- The socio-economic costs of bovine tuberculosis