Foot and mouth disease
Foot and mouth disease
Foot and mouth disease (FMD) is a highly contagious viral disease that primarily affects cloven-hooved livestock and wildlife. Although adult animals generally recover, the morbidity rate is very high in naive populations, and significant pain and distress occur in some species.
STAR-IDAZ is a partner in the Global Foot-and-Mouth Research Alliance (GFRA) which aims to establish and sustain global research partnerships to generate scientific knowledge and discover the tools for prevention, control, and eradication of FMD. The current state of FMD research is covered in the Annual state-of-the art report on animal health research on IRC priorities.
Three FMD Roadmaps have been created for development of diagnostic tests, control strategies and candidate vaccines (follow the link). The roadmaps have been reviewed by the at the STAR-IDAZ IRC workshop held at the 2019 GFRA Scientific Meeting, Bangkok, Thailand, October 29-31, 2019. Participants at the workshop (others were also participating) are listed as the Working Group on this page.
Recent Articles
- Airborne transmission of Foot-and-mouth disease virus: a review of past and present perspectives.
- A scoping review of foot-and-mouth disease risk, based on spatial and spatio-temporal analysis of outbreaks in endemic settings.
- The role of wildlife in the epidemiology and control of foot-and-mouth-disease and similar transboundary (FAST) animal diseases: a review.
- Epidemiological dynamics of foot-and-mouth disease in the horn of Africa: the role of virus diversity and animal movement
- Foot and mouth disease vaccine development and challenges in inducing long-lasting immunity: trends and current perspectives.
- Selection and use of reference panels: a case study highlighting current gaps in the materials available for foot and mouth disease.
- Scientific Opinion on the assessment of the control measures for category A diseases of Animal Health Law: Foot and Mouth Disease.
- Cell culture propagation of foot-and-mouth disease virus: adaptive amino acid substitutions in structural proteins and their functional implications.
- Planning “Plan B”: the case of moving cattle from an infected feedlot premises during a hypothetical widespread FMD outbreak in the United States
- Foot-and-Mouth Disease Virus: Immunobiology, Advances in Vaccines and Vaccination Strategies Addressing Vaccine Failures-An Indian Perspective.
- Foot and mouth disease vaccine strain selection: Current approaches and future perspectives.
- Global Foot-and-Mouth Disease Research Update and Gap Analysis, Special Issue of Transboundary and Emerging Diseases
- The need for improved vaccines against foot-and-mouth disease.
- Evaluating vaccination strategies to control foot-and-mouth disease: a country comparison study
News
- Foot-and-mouth disease study may inform long-term vaccines
- FMDV: fibrils may play a key role in viral replication
- Study identifies risk factors for spread of FMDV in Asia
- Tetramer-based analysis of FMDV segments could improve vaccine effectiveness
- Study confirms pooled milk can be used for FMD surveillance
- Universal FMDV test developed
- Pirbright calculates impact of foot-and-mouth disease control in Mongolia
- Persistently infected African buffalo not a likely cause of new FMD outbreaks, researchers say
- Understanding the socioeconomic impact of Foot and mouth disease control in Kenya
- Study traces FMDV escape from Indian subcontinent
- Creating FMDV hybrids for better vaccines
Working group lead
Road Map
Interactive tool to map and prioritise research.
Fact sheets
Working group members
- Alejandra Capozzo INTA, Argentina
- David Lefebvre Sciensano, Belgium
- Richard Reeve University of Glasgow, UK
- Stéphan Zientara ANSES/ENVA, France
- Souheyla Benfrid ANSES, France
- Antonello Di Nardo The Pirbright Institute, UK
- Nick Knowles The Pirbright Institute, UK
- Tiziana Lembo University of Glasgow, UK
- Anna Munsey University of Minnesota, USA
- Katherine Scott Agricultural Research Council, South Africa
- Phaedra Eblé Wageningen Bioveterinary Research, Netherlands)
- Mariano Perez-Filgueira INTA, Argentina
- Jeremy Salt GALVmed, UK