Foot and mouth disease
Foot and mouth disease
Foot and mouth disease (FMD) is a highly contagious viral disease that primarily affects cloven-hooved livestock and wildlife. Although adult animals generally recover, the morbidity rate is very high in naïve populations, and significant pain and distress occur in some species. Where it is endemic it causes significant economic losses and restricts livestock trade. Introduction of the disease into areas previously free can result in very high losses, such as in the UK in 2001.
The Foot-and-mouth disease virus (FMDV) is a member of the genus Aphthovirus in the family Picornaviridae. There are seven major viral serotypes: O, A, C, SAT 1, SAT 2, SAT 3 and Asia 1. Serotype O is the commonest serotype worldwide. Most species of Artiodactyla order are thought to be susceptible to some degree: important livestock hosts include cattle, pigs, sheep, goats, water buffalo and yaks. Cattle are important maintenance hosts in most areas.
STAR-IDAZ is a partner in the Global Foot-and-Mouth Research Alliance (GFRA) which aims to establish and sustain global research partnerships to generate scientific knowledge and discover the tools for prevention, control, and eradication of FMD. The current state of FMD research is covered in the Annual state-of-the art report on animal health research on IRC priorities
- Foot and mouth disease vaccine strain selection: Current approaches and future perspectives.
- Global Foot-and-Mouth Disease Research Update and Gap Analysis, Special Issue of Transboundary and Emerging Diseases
- Molecular epidemiology, evolution and phylogeny of foot-and-mouth disease virus.
- The need for improved vaccines against foot-and-mouth disease.
- Evaluating vaccination strategies to control foot-and-mouth disease: a country comparison study
- Generation and characterisation of recombinant FMDV antibodies: Applications for advancing diagnostic and laboratory assays
- FMDV contagion in carrier cattle
- Detection of FMDV in milk samples: potential for disease surveillance
- Rural poverty in eastern Africa could be reduced with foot-and-mouth disease vaccination strategy
- Method developed to detect FMDV in the environment
- Two new genetic groups of Foot-and-mouth disease virus identified
- FMDV protein could be used for disease detection