Porcine reproductive & respiratory syndrome
Porcine reproductive & respiratory syndrome
PRRS (porcine reproductive and respiratory syndrome) is a viral disease characterized by two clinical presentations, reproductive impairment or failure in breeding animals, and respiratory disease in pigs of any age. PRRS was first recognized in the USA in 1987, and the causative virus identified in the Netherlands in 1991 (originally called Lelystad virus) is a member of the genus Arterivirus. The disease is a significant problem and the virus is present in most pig producing countries in the world.
Porcine reproductive and respiratory syndrome, (PRRS), also named blue ear disease, is a widespread disease affecting domestic pigs. The symptoms include reproductive failure, pneumonia and increased susceptibility to secondary bacterial infection
Vaccines for PRRS are available and should match the naturally occurring endemic strains and consequently there is an urgent need for vaccines adapted to the circulating strains. To achieve this, development of multivalent vaccines should be considered. Commercial companies in the field are interested but there are no vaccines against the more recent strains or multiple strains. There is an urgent need for an update of existing vaccines.
The current state of PRRS research is covered in the Annual state-of-the art report on animal health research on IRC priorities.
Events
Recent Articles
- Predicting vaccine effectiveness in livestock populations: A theoretical framework applied to PRRS virus infections in pigs
- New insights about vaccine effectiveness: Impact of attenuated PRRS-strain vaccination on heterologous strain transmission
- The jigsaw of PRRSV virulence
- Challenges for porcine reproductive and respiratory syndrome (PRRS) vaccine design: reviewing virus glycoprotein interactions with CD163 and targets of virus neutralization.
- Modelling the economic efficiency of using different strategies to control Porcine Reproductive & Respiratory Syndrome at herd level.
- Improved Vaccine against PRRSV: Current Progress and Future Perspective.
- Antiviral Strategies against PRRSV Infection.
- Emergence of Different Recombinant Porcine Reproductive and Respiratory Syndrome Viruses, China.
- Pigs that recover from porcine reproduction and respiratory syndrome virus infection develop cytotoxic CD4+CD8+ and CD4+CD8- T-cells that kill virus infected cells
News
- Model suggests gene editing combined with vaccination could eliminate PRRS
- Vehicles Play Important Role in PRRSV Transmission
- Pirbright partners with ECO Animal Health and The Vaccine Group to develop new PRRS vaccines
- Stem cell approach to aid vaccine development
- $3 million grant to tackle costly pig virus
- PRRSV: strains of low and high virulence compared
- Feed additives may stop the spread of viral diseases in pigs
- Early PRRS vaccination helps protect pigs through slaughter
- Study on PRRS Focuses on Biosecurity Procedures that Make a Difference
- Gene-edited pigs resistant to PRRS viral infection