Tag: avian influenza viruses

Avian influenza viruses can combine two techniques to evade vaccine immunity

A study by researchers at The Pirbright Institute reveals more clues about how avian influenza viruses can evade vaccine immunity, aiding their spread in the field. The findings are published in Emerging Microbes and Infections. Influenza viruses are able to mutate, which can enable them to evade immunity generated by natural infection or vaccination. Influenza […]

H7N9 avian influenza viruses: mutations found to increase threat to poultry, but reduce pandemic potential

Mutations in the H7N9 avian influenza virus increase its replication rate and stability in avian cells, but reduce its preference for infecting human cells, a study from The Pirbright Institute has found. The results show that outbreaks in birds caused by strains with these mutations could pose a lower risk to human health, while remaining […]

Chicken cells gene-edited to resist Influenza A virus

Scientists have used gene-editing techniques to stop Influenza A virus from replicating in chicken cells in vitro. They speculate in the journal eLife that it might be possible to generate a gene-edited chicken that is resilient to influenza. Researchers at Imperial College London found that during an infection, Influenza A viruses hijack the cell protein […]

Mutant H9N2 avian influenza viruses show enhanced zoonotic potential

Research led by The Pirbright Institute has shown that mutant influenza A(H9N2) viruses isolated from Pakistan are able to escape immune responses and adapt to infect humans. This could result in reduced vaccine efficiency in poultry and the possibility of human outbreaks. The researchers report in Emerging Infectious Diseases the discovery of small changes to […]