Tag: Influenza A virus

A single Influenza A virus protein can increase period of infection

Research led by scientists at The Pirbright Institute has shown how an Influenza A virus (IAV) accessory protein, PB1-F2, is able to shut down two pathways of the chicken immune response to increase the length of time the virus can be transmitted. The researchers say that the majority of avian IAV isolates are able to […]

Mutant H9N2 avian influenza viruses show enhanced zoonotic potential

Research led by The Pirbright Institute has shown that mutant influenza A(H9N2) viruses isolated from Pakistan are able to escape immune responses and adapt to infect humans. This could result in reduced vaccine efficiency in poultry and the possibility of human outbreaks. The researchers report in Emerging Infectious Diseases the discovery of small changes to […]

Local immune response to Influenza studied in pigs

Researchers from The Pirbright Institute, University of Bristol, Cardiff University and University of Oxford have developed tools to show how CD8 (killer) T cells in pigs are recruited in large numbers in the lung after infection with influenza or aerosol vaccination. The tools can also be used to identify virus proteins that are recognised by […]