Tag: Influenza A virus
Influenza Virus Gap Analysis Workshop,
The Influenza Virus Gap Analysis Workshop reviewed the current state of knowledge on animal influenza, the gaps in our knowledge and where future research should be focused. The meeting was held in the light of more than 3000 outbreaks of H5N1 strain of the virus in poultry in dozens of countries, and more than 77 […]
Animal Influenza Gap Analysis Workshop, Ames, Iowa, USA
Organised by USDA ARS and STAR-IDAZ IRC
Avian influenza viruses can combine two techniques to evade vaccine immunity
A study by researchers at The Pirbright Institute reveals more clues about how avian influenza viruses can evade vaccine immunity, aiding their spread in the field. The findings are published in Emerging Microbes and Infections. Influenza viruses are able to mutate, which can enable them to evade immunity generated by natural infection or vaccination. Influenza […]
Chicken cells gene-edited to resist Influenza A virus
Scientists have used gene-editing techniques to stop Influenza A virus from replicating in chicken cells in vitro. They speculate in the journal eLife that it might be possible to generate a gene-edited chicken that is resilient to influenza. Researchers at Imperial College London found that during an infection, Influenza A viruses hijack the cell protein […]
A single Influenza A virus protein can increase period of infection
Research led by scientists at The Pirbright Institute has shown how an Influenza A virus (IAV) accessory protein, PB1-F2, is able to shut down two pathways of the chicken immune response to increase the length of time the virus can be transmitted. The researchers say that the majority of avian IAV isolates are able to […]
Mutant H9N2 avian influenza viruses show enhanced zoonotic potential
Research led by The Pirbright Institute has shown that mutant influenza A(H9N2) viruses isolated from Pakistan are able to escape immune responses and adapt to infect humans. This could result in reduced vaccine efficiency in poultry and the possibility of human outbreaks. The researchers report in Emerging Infectious Diseases the discovery of small changes to […]
Local immune response to Influenza studied in pigs
Researchers from The Pirbright Institute, University of Bristol, Cardiff University and University of Oxford have developed tools to show how CD8 (killer) T cells in pigs are recruited in large numbers in the lung after infection with influenza or aerosol vaccination. The tools can also be used to identify virus proteins that are recognised by […]