Tag: Marek’s disease

Study identifies potential candidate genes for resistance to Marek’s disease

Scientists have identified genes strongly associated with resistance to Marek’s disease in chickens, providing a large number of potential targets for future therapies or techniques to manage the disease. Findings from the analysis also reveal details about the biology behind susceptibility to Marek’s disease virus (MDV), which could lead to more precise selective breeding strategies. […]

Genetic engineering speeds up poultry vaccine development

Scientists at The Pirbright Institute have used genetic engineering to develop a vaccine that protects birds against both Marek’s disease and avian influenza. They say the process is faster and more efficient compared to previous methods, which will allow poultry vaccine producers to rapidly update vaccine strains in order to keep up with virus evolution. […]

Marek’s disease: researchers find fat is crucial for virus infection

Scientists at The Pirbright Institute have demonstrated that production and storage of fat is required for Marek’s disease virus (MDV) replication in chickens. Their research identifies new pathways that are involved in the development of the disease; they hope their findings will lead to control strategies to reduce virus spread. Marek’s disease is a major […]

Recombinant viral vector for poultry vaccination

Researchers at The Pirbright Institute have developed a new recombinant viral vector-based vaccine that is effective against both Marek’s disease (MD) and infectious bursal disease (IBD). Their study is published in npj Vaccines. Many poultry vaccines currently use a modified herpesvirus of turkeys (HVT) to induce protection. Although these vaccines are effective when used alone, […]