Tag: Porcine reproductive and respiratory syndrome virus

Vehicles play an important role in PRRSV transmission

Researchers from North Carolina State University modelled different potential transmission routes for porcine reproductive and respiratory syndrome virus (PRRSV), and found that vehicles used to move not only animals, but also farm workers and feed, can be carriers for disease spread. Their findings are published in Transboundary and Emerging Diseases. The researchers modelled nine modes […]

Stem cell lines to aid study of host-pathogen interactions in pigs

A method of producing immune cells from stem cells for research into pig infectious diseases is affordable, practical and ethical, a study led by scientists from the Roslin Institute suggests. The use of porcine pluripotent stem cell lines as a source of macrophages, is described in BMC Biology. Investigations using the technique will benefit from […]

North American PRRS Symposium

Held as part of the CRWAD 2021 Conference.

Gut microbiome associated with PRRS vaccine efficacy

A study led by researchers at Kansas State University aimed to identify gut microbiome characteristics associated with improved outcome in pigs immunized against porcine reproductive and respiratory syndrome virus (PRRSV), after co-infection with PRRSV and porcine circovirus type 2 (PCV2). “Our latest work is focused on how the gut microbiome impacts the response of growing […]

ZMAC cell line may improve isolation of PRRSV from clinical samples

A study published in the Journal of Clinical Microbiology shows that a new cell line may offer a better alternative to the cell line most commonly used to isolate porcine reproductive and respiratory syndrome virus (PRRSV) for diagnostics, research, and vaccine production. The findings could lead to more reliable processes for creating autogenous vaccines, although […]

Antibody response to PRRSV vaccination may help predict reproductive performance in sows

Measuring antibody response to vaccination against porcine reproductive and respiratory syndrome virus (PRRSV) could better predict sow reproductive success than common genetic selection strategies, according to research conducted at Iowa State University. The findings are published in Frontiers in Genetics. Genetic selection in purebred herds is the primary strategy the pig industry uses to improve […]

Role of the stable fly as a vector of pig pathogens

A Vetmeduni Vienna study investigated stable flies (Stomoxys calcitrans) from Austrian pig farms for the presence of defined swine pathogens. The findings are published in Microorganisms. The blood-sucking insect is frequently found on farms and has direct and indirect influences on animal health. Direct influences can include restlessness, pain due to biting, stress, loss of […]

Small molecules block PRRSV from infecting pig cells

Researchers at the University of Connecticut have identified compounds that can block porcine reproductive and respiratory syndrome virus (PRRSV) from infecting pig cells, creating a promising pathway to an alternative treatment. Their findings are published in Virology Journal. CD163, expressed in pig monocytes and macrophages, is a key receptor for PRRSV infection. The University of […]

Model predicts effectiveness of livestock vaccines

Scientists at The Roslin Institute have developed an epidemiological model to investigate the effectiveness of vaccines for preventing, mitigating or eliminating infectious diseases in livestock. When appropriately applied, even imperfect vaccines can prevent, eliminate or largely reduce the prevalence of viruses, the model shows. The goal of effective vaccination is not only to protect individuals […]

PRRSV: strains of low and high virulence compared

A research group from the University of Córdoba, led by Professor Librado Carrasco, has been researching Porcine reproductive and respiratory syndrome virus (PRRSV) for years, with the aim of developing effective vaccines. Although PRRSV was discovered in the 1990s, in recent years more virulent strains have emerged. As each strain behaves differently, developing effective vaccines […]