Influenza roadmap:
Diagnostic Tests
Roadmap for the development of diagnostic test for influenza
Download Influenza-diagnostic-development-roadmap5
Host response
Host response
Research Question
- Identify a measurable host response
Research Gaps and Challenges
- Complexity of interwoven factors
- Inherent variability of maternal antibodies
- Varying types of antibodies, deltaFcIgY and their roles, mucosal immunity
- Need for animal models in the laboratory
- Many different wild bird species as a host to understand
Solution Routes
- Antibody detection vs. Protection, methods for hi throughput HIs?
- Other?
- Utility of in vitro systems
Dependencies
- Avian immunology for various species
- Understanding of the immune system of migrating birds
- Research facilities that can house dams, mares, hens and not just their offspring
- Understanding the nature and effectors of resilient AIV immunity
- Factors that contribute to failure to mount such immune responses in a species-dependent manner
Projects
What activities are planned or underway?
Development of Vaccines for HPAI in Cattle, Turkey, Pigs, and Small Ruminants and Food Safety Studies Related to HPAI Virus in Food Products
Planned Completion date 25/08/2029
Source Countries:
United States
Intervention Strategies to Control Endemic and New and Emerging Influenza A Virus Infections in Swine
Planned Completion date 04/10/2026
Source Countries:
United States