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Influenza roadmap:
Control Strategies

Roadmap for the development of disease control strategies for influenza

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Resistant/cleared

Resistant/cleared

Research Question

  • Information on resistant species (innate mechanisms of resistance to infection) and on immune clearance in susceptible species

Research Gaps and Challenges

  • Genetic determinants of resistance to HPAI strains in known reservoir species (e.g. ducks)
  • Mechanisms (genetic or otherwise) behind duck resistance to HPAI strains
  • Translation of recent findings on possible innate immune determinants of susceptibility in avian species into generation of more resistant breeds
  • Understanding avian immunology across 9000 species

Solution Routes

  • Understanding the immune response to influenza viruses and viral clearance with various strains, hosts, ages, states of immune function
  • The state of influenza A viruses in migrating wild birds
  • Role of deltaFcIGY in neutralization/clearance

Dependencies

  • Data on immunity from field settings
  • Approved tests (better tests) to assess immunity and protection from challenge

Projects

What activities are planned or underway?

Risk and economic consequences of contagious animal disease introduction

Planned Completion date 18/10/2024

Source Countries:

NetherlandsIconNetherlands

Dynamics of sustainability in integrated agriculture : aquaculture systems in the Mekong Delta

Planned Completion date 21/10/2024

Source Countries:

NetherlandsIconNetherlands