Influenza roadmap:
Control Strategies
Roadmap for the development of disease control strategies for influenza
Download Influenza-control-development-roadmap10
Coinfection
Next steps
Coinfection
Research Question
- Impact of influenza virus infection on co-infection with different viruses or bacteria and vice versa
Research Gaps and Challenges
- Effects of co-infection with different viruses or bacteria
- Coinfection often leads to misdiagnosis
- Coinfection could lead to reassortment, increase shedding and increase susceptibility?
Solution Routes
- Experimental and field studies particularly with representative avian species (wild & poultry species) and for pigs
- Assess added value of vaccination against co-infecting pathogens to prevent influenza infections
- Models that include coinfection risks/phenotypes/outcomes and
- Suitable panel assay for respiratory viruses
- Whole genome sequencing in co-infected populations to identify the possible pathogens that could dampen the immune system and result in persistent low-level infections
- Investigate regional approach instead of country-level approach in territories with similar trade systems
- Understanding market system and role in co-infection and vice versa
- Penside tests for co-infections to improve field actions
Dependencies
- Knowledge of/studies of the potential co-infectors across the globe
- Good differential diagnosis protocols
- Improved tests to inform/predict protection
- Well developed and integrated vaccination programs
Projects
What activities are planned or underway?
Impact of host age on viral and bacterial communities in a waterbird population.
Planned Completion date 01/11/2022
Source Countries:
Netherlands
Association of biosecurity and hygiene practices with avian influenza A/H5 and A/H9 virus infections in turkey farms.
Planned Completion date 14/03/2024
Source Countries:
Netherlands