Mycoplasmas including CBPP/CCPP roadmap:
Vaccines
Research roadmap for contagious bovine pleuropneumonia (CBPP) vaccine development
Download CBPP vaccine development roadmap final10
Expression system
Expression system
Research Question
- Identify heterologous gene expression systems that can express recombinant Mmm antigens which resemble native immunogens.
Research Gaps and Challenges
- Lack of in vitro reagents and assays to guide immunogen design.
- Expression of proteins that resemble native antigens.
Solution Routes
- Express antigens in a non-virulent strain of mycoplasma.
Dependencies
- Identity of a range of candidate vaccine antigens.
State Of the Art
- A few experimental vaccine antigens have been identified.
Projects
What activities are planned or underway?
Collaborative project: Stressless examination for pathogens associated with bovine respiratory disease complex Stressless fUtuRE – subproject B (SURE)
Planned Completion date 31/05/2024
Source Countries:
Denmark
Collaborative project: Stressless examination for pathogens associated with bovine respiratory disease complex Stressless fUtuRE – subproject A (SURE)
Planned Completion date 31/05/2024
Source Countries:
Denmark