Influenza roadmap:
Control Strategies
Roadmap for the development of disease control strategies for influenza
Download Influenza-control-development-roadmapC
Resistant/cleared
Resistant/cleared
Research Question
- Information on resistant species (innate mechanisms of resistance to infection) and on immune clearance in susceptible species
Research Gaps and Challenges
- Genetic determinants of resistance to HPAI strains in known reservoir species (e.g. ducks)
- Mechanisms (genetic or otherwise) behind duck resistance to HPAI strains
- Translation of recent findings on possible innate immune determinants of susceptibility in avian species into generation of more resistant breeds
- Understanding avian immunology across 9000 species
Solution Routes
- Understanding the immune response to influenza viruses and viral clearance with various strains, hosts, ages, states of immune function
- The state of influenza A viruses in migrating wild birds
- Role of deltaFcIGY in neutralization/clearance
Dependencies
- Data on immunity from field settings
- Approved tests (better tests) to assess immunity and protection from challenge
Projects
What activities are planned or underway?
Development of Vaccines for HPAI in Cattle, Turkey, Pigs, and Small Ruminants and Food Safety Studies Related to HPAI Virus in Food Products
Planned Completion date 25/08/2029
Source Countries:
United States
Automated non-invasive Detection of Surface Contamination and Optimizing Surface Biofilm Removal Conditions in Large-Scale Food Processing Equipment
Planned Completion date 31/08/2028
Source Countries:
United States