Influenza roadmap:
Control Strategies
Roadmap for the development of disease control strategies for influenza
Download Influenza-control-development-roadmapC
Resistant/cleared
Resistant/cleared
Research Question
- Information on resistant species (innate mechanisms of resistance to infection) and on immune clearance in susceptible species
Research Gaps and Challenges
- Genetic determinants of resistance to HPAI strains in known reservoir species (e.g. ducks)
- Mechanisms (genetic or otherwise) behind duck resistance to HPAI strains
- Translation of recent findings on possible innate immune determinants of susceptibility in avian species into generation of more resistant breeds
- Understanding avian immunology across 9000 species
Solution Routes
- Understanding the immune response to influenza viruses and viral clearance with various strains, hosts, ages, states of immune function
- The state of influenza A viruses in migrating wild birds
- Role of deltaFcIGY in neutralization/clearance
Dependencies
- Data on immunity from field settings
- Approved tests (better tests) to assess immunity and protection from challenge
Projects
What activities are planned or underway?
Impact of host age on viral and bacterial communities in a waterbird population.
Planned Completion date 01/11/2022
Source Countries:
Netherlands
Association of biosecurity and hygiene practices with avian influenza A/H5 and A/H9 virus infections in turkey farms.
Planned Completion date 14/03/2024
Source Countries:
Netherlands