Foot and Mouth Disease roadmap:
Vaccines
Roadmap for the development of candidate vaccines for FMD
Download FMD Vaccine Lead Summaries_Roadmap updateB
Replication
Establishing how FMDV replicates in the cell
Research Question
What are we trying to achieve and why? What is the problem we are trying to solve?
To generate knowledge on virus replication
Research Gaps and Challenges
What are the scientific and technological challenges (knowledge gaps needing to be addressed)?
- Investigate virus replication at the point of entrance in animals (how to prevent replication at the primary sites)
- Investigate the mechanisms that lead to the formation of vesicles and how the infection carries on
Solution Routes
What approaches could/should be taken to address the research question?
Dependencies
What else needs to be done before we can solve this need?
State Of the Art
Existing knowledge including successes and failures
Projects
What activities are planned or underway?
Practical surveillance guidelines for the progressive control of Food-and-Mouth Disease and other transboundary animal diseased
Planned Completion date 20/09/2024
Source Countries:
Netherlands
Foot-and-mouth disease virus antigenic landscape and reduced immunogenicity elucidated in atomic detail.
Planned Completion date 10/10/2024
Source Countries:
Netherlands