Influenza roadmap:
Vaccines
Roadmap for the development of candidate vaccines for influenza
Download Influenza-vaccine-development-roadmapA
Entry
Entry
Research Question
- Understanding the mechanism of virus entry
Research Gaps and Challenges
- Lack of knowledge on cleavage sites for HPAI and LPAI
Solution Routes
- Basic research on pathogenesis – how
- Knowledge on multi-basic cleavage site of haemagglutinin of H5 and H7 subtypes of AIV
- Develop approaches to correlate expression of sialic acid (SA) receptor in different tissues with adaptation or restriction to AIV subtypes infection and shedding pattern in different species
- Identify other factors for host adaptations
Projects
What activities are planned or underway?
US-UK Collab: Avian influenza virus in cattle, a framework for forecasting transmission dynamics of zoonotic disease in livestock systems
Planned Completion date 31/01/2030
Source Countries:
United States
PARTNERSHIP:Harnessing Bovine Organoids to Advance HPAI Influenza A Virus Research
Planned Completion date 14/03/2029
Source Countries:
United States