Roadmap for the development of diagnostic tests for FMD

What are we trying to achieve and why? What is the problem we are trying to solve?

To define immunological parameters involved in immune response against homologous and heterologous infection, besides antibody titres.

What are the scientific and technological challenges 
(knowledge gaps needing to be addressed)?

• Confirmation of the infection status, including the detection of infection at the earliest possible stage

What approaches could/should be taken to address the research question?

Characterisation of the cellular immune responses during the different stages of infection and comparison with the antibody response.

What else needs to be done before we can solve this need?

• Host-pathogen interaction
• FMDV genome