Influenza roadmap:

Diagnostic Tests

Roadmap for the development of diagnostic test for influenza

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Sample type/transportation/preparation

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Next steps

Sample type/transportation/preparation

Research Question

Improvement of viral sampling, transportation and isolation of nucleic acids and viruses

Research Gaps and Challenges

Sampling sparing methods
Improvement of safe transport of virus
Pools and matrix of choice for environmental sampling, Virus extraction from environmental matrices (e.g. water, mud, aquatic microfauna, etc.)
Poultry environs that also include varying types of chemicals
Limitations defined by CITES (species protection and conservation acts)
Limitations defined by the NAGOYA protocol (WHO exemptions etc.)
Preserve the quality and viability of biological samples during transportation over long distances and temperature extremes

Solution Routes

In-field extraction and diagnostics (PoC/Penside) to minimize transport
Development of transport media that stabilize the virus without refrigeration
Non-invasive samples from wild birds
Non-invasive samples from swine
Environmental sampling methods including
– Air sampling and analysis protocols
– Waste water
– Poultry house sampling, where are the best samples

Dependencies

Standardize environmental sampling procedures
Easy legal frameworks for transport
Manageable CITES and NAGOYA rules for avian samples
Data management for sampling/testing coordination
Human resources

Projects

What activities are planned or underway?

Development of Vaccines for HPAI in Cattle, Turkey, Pigs, and Small Ruminants and Food Safety Studies Related to HPAI Virus in Food Products

Planned Completion date 25/08/2029

Source Countries:

United States

Automated non-invasive Detection of Surface Contamination and Optimizing Surface Biofilm Removal Conditions in Large-Scale Food Processing Equipment

Planned Completion date 31/08/2028

Source Countries:

United States

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