Influenza roadmap:
Vaccines
Roadmap for the development of candidate vaccines for influenza
Download Influenza-vaccine-development-roadmap6
Subunit vaccines
Subunit vaccines
Research Question
- Immunogenic subunit vaccines and optimal expression systems
Research Gaps and Challenges
- Low immunogenicity
- Can be developed as multivalent with several mixture of antigens.
- Cost effective
- Still fairly empirical with respect to success of in the antigenic/stability
properties of the antigens - Adjuvants in general (killed vaccines and other vaccine platforms) need
further research
Solution Routes
- Use of adjuvants that could increase immunogenicity
- Production and trial of the most suitable antigens
Dependencies
- Develop adjuvants that could increase immunogenicity
- For commercialization, adjuvant withdrawal time is a major hurdle
depending on species and use
State Of the Art
- Baculous virus
Projects
What activities are planned or underway?
Development of Vaccines for HPAI in Cattle, Turkey, Pigs, and Small Ruminants and Food Safety Studies Related to HPAI Virus in Food Products
Planned Completion date 25/08/2029
Source Countries:
United States
Automated non-invasive Detection of Surface Contamination and Optimizing Surface Biofilm Removal Conditions in Large-Scale Food Processing Equipment
Planned Completion date 31/08/2028
Source Countries:
United States