Brucellosis
Brucellosis
Brucellosis, a bacterial disease caused by organisms in the genus Brucella, is an important zoonosis and a significant cause of reproductive losses in animals. The current members of this genus include Brucella abortus, B. melitensis, B. suis and B. ovis in livestock. Other species affect dogs, marine mammals, and wild rodents. Most species of Brucella circulate in a limited number of reservoir hosts, but other animals can be infected, especially when they are in close contact. People infected with brucellae may suffer from a debilitating nonspecific illness or localized involvement of various organs.
Cattle are the commonest reservoir hosts for B. abortus, but a few other species including water buffalo, bison, and African buffalo can also maintain this organism. Sheep and goats are the usual hosts for B. melitensis. B. ovis is mainly a pathogen of sheep and also circulates in captive red deer in New Zealand. B. suis biovars 1 and 3 are mainly found in domesticated and feral pigs, and other biovars of B. suis are found in wild boar, caribou and reindeer, and in wild rodents.
Brucellosis is an important zoonotic disease and is sometimes referred to as a neglected disease of humans. The worldwide economic losses due to brucellosis are extensive not only in animal production but also in human health. It is common in developing countries where people live in close proximity to their flocks and herds and is considered a ‘One-health’ issue. STAR-IDAZ IRC has developed a Roadmap to identify research gaps and control the disease. Click on the link.
Recent Articles
- Brucellosis and One Health: Inherited and Future Challenges.
- A systematic review of economic assessments for brucellosis control interventions in livestock populations.
- Evaluation of brucellosis vaccines: a comprehensive review.
- Accuracy of molecular diagnostic methods for the detection of bovine brucellosis: a systematic review and meta-analysis.
- The perspective of antibiotic therapeutic challenges of brucellosis in the Middle East and north African countries: current situation and therapeutic management.
- Comparative review of brucellosis in small domestic ruminants.
- Global comprehensive literature review and meta-analysis of Brucella spp. in swine based on publications from 2000 to 2020.
- Immunoproteomics of Brucella abortus reveals potential of recombinant antigens for discriminating vaccinated from naturally infected cattle.
- Bovine brucellosis - a comprehensive review.
- Brucellosis in wildlife in Africa: a systematic review and meta-analysis.
- Contamination of milk and dairy products by Brucella species: A global systematic review and meta-analysis.
- Animal brucellosis control or eradication programs worldwide: A systematic review of experiences and lessons learned.
- Brucellosis in West and Central Africa: A review of the current situation in a changing landscape of dairy cattle systems.
- Caprine brucellosis: A historically neglected disease with significant impact on public health.
- A systematic review of current immunological tests for the diagnosis of cattle brucellosis.