Projects
ASSESSING THE MICROBIOME AS A TOOL FOR THE MITIGATION OF VIRAL DISEASE IN NURSERY PIGS
Summary
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<b>Animal Health Component</b>
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<b>Research Effort Categories</b><br>
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Objectives & Deliverables
<b>Project Methods</b><br> A randomized controlled viral challenge study will be used to generate data regarding the role and efficacy of fecal microbiome transplantation on swine health and production outcomes. During the trial, multiple tissue samples will be taken longitudinally from study pigs and subjected to several methods including immunological assays (to assess host response) and microbiome assays (to assess microbiome profiles before, during and after challenge and treatments). Pig health and performance will be measured throughout the trial. Data will be analyzed using multivariable time series analysis to understand how treated versus control pigs differ in their response to the viral challenge. Any microbes found to be strongly protective against clinical disease and/or death will be subjected to available culture methods in order to establish an isolate bank of "top candidate" protective microbes.
Principle Investigator(s)
Planned Completion date: 31/05/2025
Effort: $237,204.00
Project Status
ACTIVE
Principal Investigator(s)
National Institute of Food and Agriculture
Researcher Organisations
UNIV OF MINNESOTA
United Kingdom