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Influenza roadmap:
Diagnostic Tests

Roadmap for the development of diagnostic test for influenza

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4

Stage specific response
    "] --> 21455["

    3

    Technology optimization
      "] 21463["

      6

      Biomarkers
        "] --> 21455["

        3

        Technology optimization
          "] 21464["

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          Characterization
            "] --> 21455["

            3

            Technology optimization
              "] 21455["

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              Technology optimization
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                2

                Validation/ proficiency
                  "] 21453["

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                  Validation/ proficiency
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                    1

                    Fit-for-purpose diagnostic tool
                      "] 21460["

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                      Host response"] --> 21463["

                      6

                      Biomarkers
                        "] 21470["

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                        Organism detection"] --> 21463["

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                        Biomarkers
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                          Host-pathogen interaction
                          • ASusceptible
                          • BExposed
                          • CInfectious
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                          Host response"] 21460["

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                          Host response"] --> 21457["

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                          Stage specific response
                            "] 21473["

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                            Sample type/transportation/preparation
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                              7

                              Host-pathogen interaction
                              • ASusceptible
                              • BExposed
                              • CInfectious
                              "] 21473["

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                              Sample type/transportation/preparation
                                "] --> 21470["

                                9

                                Organism detection"] 21470["

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                                Organism detection"] --> 21464["

                                8

                                Characterization
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                                  Lead Summary Challenges and gap analysis
                                  1 Fit-for-purpose diagnostic tool Diagnostic
                                  3 Technology optimization Technology optimization
                                  2 Validation/ proficiency Validation
                                  6 Biomarkers Biomarkers
                                  8 Characterization Characterization
                                  5B Cell mediated immunity Cell-mediated immunity
                                  5A AB response Antibody response
                                  5 Host response Host response
                                  7C Infectious
                                  7B Exposed
                                  7A Susceptible
                                  7 Host-pathogen interaction Host-pathogen interaction
                                  9B Genetic Genetic
                                  9A Direct detection Direct detection
                                  9 Organism detection Organism detection
                                  10 Sample type/transportation/preparation Sample type/transportation/preparation
                                  4 Stage specific response Disease stage specific response