Tag: Foot-and-mouth disease virus
Study provides new insight into the immune pathogenesis of FMDV
Researchers at the Pirbright Institute and the Roslin Institute have discovered how foot-and-mouth disease virus (FMDV) interacts with immune cells in lymphoid tissues, helping the virus to persist in animals such as African buffalo. Their findings are reported in PLoS Pathogens. In studies in mice, they found that FMDV binds to follicular dendritic cells, which […]
FMDV: fibrils may play a key role in viral replication
Researchers have used cryo-electron microscopy to observe tiny structures created by foot-and-mouth disease virus (FMDV). Biologists from the University of Leeds in collaboration with colleagues at the MRC-University of Glasgow Centre for Virus Research, observed the interaction between components of the virus in test tube experiments under bio-secure conditions. High-resolution images revealed the formation of […]
Scientific meeting of the Global Foot and Mouth disease Research Alliance
the VI Global Foot-and-Mouth Disease Research Alliance (GFRA) Scientific Meeting to be held virtually due to the COVID-19 pandemic, from 1 – 3 November 2021. Registration is open. https://www.gfra2021.com/registrations The GFRA Meeting 2021 will last three days, and every day will include one or two plenary lectures (~20 min), and oral sessions held by invited speakers (~15 min) […]
Scientific meeting of the Global Foot and Mouth disease Research Alliance, Buenos Aires, Argentina
This meeting of leading scientists will bring together a broad range of international researchers who will share their diverse research issues in foot and mouth disease
Tetramer-based analysis of FMDV segments could improve vaccine effectiveness
Researchers from The Pirbright Institute have identified new parts of foot-and-mouth disease virus (FMDV) that stimulate an immune response. Their findings, reported in Immunology, could be used to inform the design of improved vaccines. They also discovered that T helper cells were present in cattle samples four years after the animals had been vaccinated, indicating […]
Case of FMDV in dogs after eating infected meat
A case report filed by scientists at The Pirbright Institute details the first instance of naturally acquired foot-and-mouth disease virus (FMDV) infection in dogs. In this unusual case reported in BMC Veterinary Research, FMDV was identified in a sample of heart tissue received by Pirbright’s diagnostic laboratory, the World Reference Laboratory for Foot-and-Mouth Disease (WRLFMD). […]
Environmental transmission of foot-and-mouth disease virus
Scientists at The Pirbright Institute and Wageningen Bioveterinary Research have demonstrated that environments contaminated with foot-and-mouth disease virus (FMDV) could potentially infect animals up to 14 days after removing infected cattle, providing evidence that should lead to more effective outbreak containment methods. While FMDV is spread through direct contact between animals, the virus can also […]
Universal FMDV test developed
A diagnostic test that can detect whether an animal has been infected by or vaccinated against any type of Foot-and-mouth disease virus (FMDV) has been developed by scientists at The Pirbright Institute and Istituto Zooprofilattico Sperimentale della Lombardia e dell’Emilia Romagna (IZSLER). The test could be used in countries where foot-and-mouth disease (FMD) outbreaks are […]
Research sheds new light on molecular evolution of Foot-and-mouth disease virus
Research from The Pirbright Institute has shown that different populations of Foot-and-mouth disease virus (FMDV) swap sections of genetic material at a far higher rate than originally thought. It was previously believed that FMDV evolution is mainly driven by mutations caused by small copying errors that accumulate in the RNA genome of the virus when […]
Preclinical transmission of Foot-and-mouth disease virus studied in pigs
Foot-and-mouth disease virus (FMDV) spreads much more aggressively in pigs than previous research suggests, according to a study by U.S. Department of Agriculture (USDA) scientists. The study, published in Scientific Reports, shows that pigs infected with FMDV were highly contagious to other pigs just 24 hours after infection – long before showing any clinical signs […]