Brucellosis roadmap:
Vaccines
Roadmap for development of a candidate vaccine for Brucella
Download Roadmap-for-a-brucella-vaccine-v15
Development of a DNA vaccine for Brucellosis
Dependencies
Next steps
DNA/RNA Vaccines
Research Question
- The development of an effective DNA vaccine for use on its own or in combination with other Brucella vaccines in a prime-boost combination.
Solution Routes
- Establishing the immune responses following immunisation with DNA coding for various protective antigens.
- Challenge experiments involving animals vaccinated with DNA fragments identified from experiments looking at the immune responses.
Dependencies
- Identifying a combination of protective antigens the genes for which could form part of a DNA vaccine
- Identifying suitable molecular adjuvants to stimulate strong cell-mediated immune responses
Projects
What activities are planned or underway?
An overview of current approaches and challenges to the control of endemic infectious cattle diseases in Albania
Planned Completion date 14/07/2021
Source Countries:
Netherlands
Would you bet on the vet? Influences on dairy farmers' vaccination choices, with a spotlight on the Veterinarian impact.
Planned Completion date 01/01/2024
Source Countries:
Netherlands