Brucellosis roadmap:
Vaccines
Roadmap for development of a candidate vaccine for Brucella
Download Roadmap-for-a-brucella-vaccine-v19
Identifying suitable delivery systems for subunit vaccine candidates, killed bacteria and DNA vaccine candidates
Dependencies
Next steps
- 4 Development of a killed/inactivated Brucella vaccine
- 4A Safety
- 4B Delivery Route
- 4C Delivery Platform
- 4D Efficacy in Challenge Model
- 5 Development of a DNA vaccine for Brucellosis
- 5A Safety
- 5B Delivery Route
- 5C Delivery Platform
- 5D Efficacy in Challenge Model
- 6 Development of a Brucella subunit vaccine
- 6A Safety
- 6B Delivery Route
- 6C Delivery Route
- 6D Efficacy in Challenge Model
Adjuvant
Research Question
- Generation of an optimal immune response to the various sub-unit candidates, killed bacteria and DNA candidates
Solution Routes
- Immune response to antigens delivered on Nanoparticles
- Immune response following inclusion of various adjuvants with the candidate vaccines
- Molecular adjuvants for DNA candidates
Dependencies
- Identity of protective mechanism and antigens
Projects
What activities are planned or underway?
An overview of current approaches and challenges to the control of endemic infectious cattle diseases in Albania
Planned Completion date 14/07/2021
Source Countries:
Netherlands
Would you bet on the vet? Influences on dairy farmers' vaccination choices, with a spotlight on the Veterinarian impact.
Planned Completion date 01/01/2024
Source Countries:
Netherlands