Brucellosis roadmap:
Vaccines
Roadmap for development of a candidate vaccine for Brucella
Download Roadmap-for-a-brucella-vaccine-v13
Development of a novel Brucellosis attenuated vaccine allowing DIVA
Dependencies
Next steps
Rationally Attenuated Candidates
Research Question
- The development of a novel attenuated vaccine that gives better protection and/or improved safety than current vaccines and allows differentiation of infected and vaccinated animals
Research Gaps and Challenges
- Which strain of the various Brucella species to start with
Solution Routes
- Establishing the immune responses to genetically modifies Brucella organisms
- Challenge experiments involving animals vaccinated with candidate organisms
Dependencies
- The generation of GM organisms where the genes for selected virulence factors have been removed
Projects
What activities are planned or underway?
An overview of current approaches and challenges to the control of endemic infectious cattle diseases in Albania
Planned Completion date 14/07/2021
Source Countries:
Netherlands
Would you bet on the vet? Influences on dairy farmers' vaccination choices, with a spotlight on the Veterinarian impact.
Planned Completion date 01/01/2024
Source Countries:
Netherlands