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Vaccines

Roadmap for development of a candidate vaccine for Brucella

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Development of a Brucella subunit vaccine

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Dependencies

Next steps

Subunit Vaccines

Research Question

  • The development of an effective subunit vaccine for use on its own or in combination with other Brucella vaccines in a prime-boost combination

Solution Routes

  • Establishing the immune responses to the various subunits
  • Challenge experiments involving animals vaccinated with subunit candidate vaccines that resulted in interesting immune responses.
  • Establishing that there isn’t interference between the various antigens

Dependencies

  • The availability of suitable adjuvants to stimulate strong cell-mediated immune responses
  • Identifying expression systems that give correct Antigen conformation

Projects

What activities are planned or underway?

Estimates of disease burden caused by foodborne pathogens in contaminated dairy products in Rwanda.

Planned Completion date 06/04/2023

Source Countries:

NetherlandsIconNetherlands

An overview of current approaches and challenges to the control of endemic infectious cattle diseases in Albania

Planned Completion date 14/07/2021

Source Countries:

NetherlandsIconNetherlands