Tag: vaccine development

IVIS2022: 13th International Veterinary immunology Symposium, South Africa, 8-12 August 2022

The symposium is held every three years in association with the International Congress of Immunology and brings Industry, Government, and Academic specialists together to provide an update and overview of new, cutting-edge information in basic and applied veterinary immunology. Topics include protective immunity, vaccine strategies, and important disease targets in various animal species. The IVIS […]

New DIVA vaccine candidates against peste des petits ruminants virus

Two new vaccine candidates that could differentiate between vaccinated and infected animals and contribute to the goal of global eradication of peste des petits ruminants virus (PPRV) have been developed by researchers at The Pirbright Institute. In a study published in Viruses, researchers explored ways to create live attenuated DIVA (Differentiating Infected from Vaccinated Animals) […]

Research aims to improve enzootic abortion vaccines

A vaccine being developed against ovine enzootic abortion by scientists at the Moredun Research Institute has shown promising results in laboratory trials, being able to protect against abortion caused by Chlamydia abortus without the risk of causing infection in the animal. The results of the study are published in Vaccines. Ovine enzootic abortion is a […]

Improved poultry influenza vaccine provides rapid protection

A vaccine developed by researchers at The Pirbright Institute triggers a rapid immune response which protects chickens against signs of disease and reduces virus shedding. The researchers say the vaccine would also be easier and less costly to produce than the traditional influenza vaccines made in chicken eggs. Many poultry influenza vaccines protect birds from […]

Cocktail of recombinant proteins protects cattle against paratuberculosis

Scientists with the USDA’s Agricultural Research Service (ARS) have developed an experimental vaccine to protect cattle from infection with Mycobacterium avium subsp. paratuberculosis (MAP). Rather than use the cells of live but weakened or dead MAP, as has been done with past commercial vaccine formulations, ARS microbiologists Judy Stabel and John Bannantine set their sights […]

Tetramer-based analysis of FMDV segments could improve vaccine effectiveness

Researchers from The Pirbright Institute have identified new parts of foot-and-mouth disease virus (FMDV) that stimulate an immune response. Their findings, reported in Immunology, could be used to inform the design of improved vaccines. They also discovered that T helper cells were present in cattle samples four years after the animals had been vaccinated, indicating […]

Veterinary Vaccinology Landscape Survey: Community Consultation

UKRI-BBSRC, on behalf of the veterinary vaccinology research funders and programme owners, are consulting the research community (including those in academia, funding agencies, industry and others) on the current veterinary vaccinology research and innovation needs, as well as the future perspectives. The overall purpose is to gain a better understanding of the priorities, gaps, and barriers […]

ASFV vaccine candidate produced in a continuous cell line

The U.S. Department of Agriculture’s Agricultural Research Service (ARS) has announced that an African swine fever virus (ASFV) vaccine candidate has been adapted to grow in a cell line, which means that those involved in vaccine production will no longer have to rely on live pigs and their fresh cells for vaccine production. “This opens […]

Infectious bronchitis virus: increasing vaccine heat resilience could improve performance

Studies from The Pirbright Institute and the University of Edinburgh’s Roslin Institute show that two vaccines against specific strains of infectious bronchitis virus (IBV) do not offer complete protection against a third strain, and that this may be partly down to the temperature range the vaccine virus can survive in. Commercial IBV vaccines are currently […]

IBDV VP4 protein dampens poultry immune response

Work carried out by scientists at The Pirbright Institute has revealed that differences in virulence between strains of Infectious bursal disease virus (IBDV) may be partly down to changes in the VP4 protein. Their findings, published in Frontiers in Cellular and Infection Microbiology, may help explain why very virulent (vv) strains cause high mortality rates […]